Depression Clinical Trials
A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 714 clinical trials
A Randomized, Double-blind, Active-controlled Trial to Assess the Efficacy and Safety of AXS-05 Administered Orally to Subjects with Treatment Resistant Major Depressive Disorder
We are currently enrolling participants for a clinical research study to look at the effectiveness and safety of an investigational medication AXS-05 (a combination of bupropion and dextromethorphan) compared to bupropion (Approved by FDA), in patients with depression who have not responded to prior treatment with at least one antidepressant. …
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- 19 Feb, 2024
- 1 location
Transcranial Magnetic Stimulation (TMS) Treatment for Post-Traumatic Stress
Evaluates novel Transcranial Magnetic Stimulation (TMS) methods for the treatment of post-traumatic stress disorder (PTSD) and depressive symptoms to determine which strategies provide the greatest benefit to patients. Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation technique FDA-approved for the treatment of major depressive disorder (MDD) and obsessive compulsive …
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- 19 Feb, 2024
- 1 location
Computer-Assisted Therapy for Depression
The purpose of this study is to learn more about the treatment success of Computer-augmented Cognitive Behavioral Therapy (CCBT) and examine the neural connections of patients with depression via functional Magnetic Resonance Imaging (fMRI) scans.Computer-augmented Cognitive Behavioral Therapy (CCBT) is approved by the FDA as a form of treatment for …
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- 19 Feb, 2024
- 1 location
DEPRESSION STUDY: INVESTIGATING LINKS BETWEEN SLEEP AND MOOD
GOAL: This research study aims to examine the role of slow-wave sleep activity in improving mood in individuals with Major Depressive Disorder (MDD).TARGET POPULATION: We are looking for 40 currently depressed males and females and 20 healthy controls with no history of depression between the ages of 25-50.
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- 19 Feb, 2024
Depression Study-- Neuroimaging and Transcranial Magnetic Stimulation (TMS)
We are recruiting individuals suffering from depression for a research study focused on the neuroscience behind depression and stress. Our study uses a mechanism called transcranial magnetic stimulation, or TMS, which is an FDA-approved treatment method for major depression.
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- 19 Feb, 2024
- 1 location
Genetics of Alcohol Dependence and Withdrawal in African Americans
The purpose of this study is to learn things that will help us better understand alcohol dependence, other kinds of substance dependence, and aspects of personality and behavior in African Americans. DNA, the material that carries genetic instructions, will be taken from blood, and used to study genes for these …
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- 19 Feb, 2024
- 4 locations
Investigating the Role of Slow-wave Activity as a Marker of Impaired Plasticity in Major Depressive Disorder
This research study aims to examine the role of sleep slow-wave activity (SWA) in modulating mood by testing the model that disrupting SWA during sleep can prevent homeostatic decreases in plasticity, thereby increasing plasticity and improving mood in individuals with MDD. Forty males and females with MDD (25-50 yo), and …
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- 19 Feb, 2024
- 1 location
Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexpiprazole as Adjunctive Therapy in the Maintenance Treatment of Adults With Major Depressive Disorder
You are being asked to take part in this study because you have been diagnosed with major depressive disorder (depression). Brexpiprazole is a medication being studied as a possible treatment for adjunctive treatment for Major Depressive Disorder (MDD).
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- 19 Feb, 2024
- 1 location
An Open-Label Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects with Major Depressive Disorder
This study is a multi-center, open-label trial to evaluate the long-term safety and efficacy of AXS-05 in subjects with major depressive disorder (MDD). Eligible subjects must have completed a prior MDD study with AXS-05 (AXS-05-301 or AXS-05-MDD-301) immediately prior to enrollment in this study.
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- 19 Feb, 2024
- 1 location
A Phase 3 Multicenter Randomized Double-blind Placebo-controlled Trial to Evaluate the Efficacy Safety and Tolerability of Brexpiprazole as Adjunctive Therapy in the Maintenance Treatment of Adults With Major Depressive Disorder
This trial is a phase 3, double-blind, placebo-controlled, randomized withdrawal maintenance trial of brexpiprazole in subjects who require adjunctive treatment of MDD designed to fulfill a post-marketing commitment to the US Food and Drug Administration (FDA). There is a paucity of data on long-term use of the combination of ADT …
- 0 views
- 19 Feb, 2024
- 1 location