Stroke Clinical Trials

A listing of Stroke medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 44 clinical trials
A Randomized Placebo-Controlled Study of the Efficacy and Safety of Intracerebral Stem Cells (CTX0E03) in Subjects with Disability Following an Ischemic Stroke

The research study is being conducted to find out if this study drug provides any improvement in the arm and/or leg function affected by the stroke. The study will also gather more information about the safety of the study drug, surgical procedure and equipment used to inject the study drug.

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  • 19 Feb, 2024
  • 1 location
Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

The purpose of this research study is to assess whether lowering of your cholesterol blood level can reduce your risk for major cardiovascular events (for example, heart attack or stroke) when evolocumab is taken in addition to your current medical therapy as directed by your doctor, which may include a …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Cardiovascular Inflammation Reduction Trial (CIRT): A randomized double-blind placebo controlled event-driven trial of weekly low-dose methotrexate (LDM) in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with type 2 diabetes or metabolic syndrome

The objective of this study is to find out if giving methotrexate at low doses to people with heart disease will prevent a second heart attack or stroke. This trial will be conducted in the US and Canada and aims at enrolling 7000 patients. Before randomization, the patients will be …

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  • 19 Feb, 2024
  • 1 location
FOLLOW-UP VESSEL WALL MR IMAGING TO EXPLORE SEX-DIFFERENCES OF INTRACRANIAL ARTERIAL WALL CHANGES AND INTRACRANIAL ATHEROSCLEROTIC PLAQUE TREATMENT EFFICACY

We propose a study to prospectively evaluate women and men with stroke using VWI to estimate the prevalence of vessel wall abnormalities leading to stroke. Early detection of vessel wall changes in correlation with modifiable risk factors will help us identify opportunities for early prevention of stroke in women.

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  • 19 Feb, 2024
  • 1 location
A randomized, open-label, comparative study for Edoxaban and Enoxaparin/Warfarin vs Warfarin alone in subjects with Atrial Fibrillation who have undergone Electrical Cardioversion

The purpose of this study is to compare edoxaban with warfarin to see if it is safe and effective in preventing thromboembolism (formation of a clot [thrombus] in a blood vessel that breaks loose and is carried by the blood stream to block another vessel) and strokes which results when …

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  • 19 Feb, 2024
  • 1 location
Transcatheter Aortic Valve Replacement to UNload the Left ventricle in patients with ADvanced heart failure

We will collect information regarding death and major events such as stroke and also ask you about your quality of life and functional status.

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  • 19 Feb, 2024
  • 1 location
The REFLECT Trial: A Randomized Evaluation oF the TriGuard HDH Cerebral Embolic Protection Device and the TriGUARD 3 Cerebral Embolic Protection Device to Reduce the Impact of Cerebral Embolic LEsions after TransCatheter Aortic Valve ImplanTation

The purpose of the study is to assess whether the TriGUARD 3 can prevent death, stroke, more subtle signs of brain injury, and/or silent brain injury as measured by a magnetic resonance imaging (MRI) study of the brain.

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  • 19 Feb, 2024
  • 1 location
PRELIMINARY STUDY OF OPTICAL BIOMARKERS FOR NEURODEGENERATION IN CHRONIC CEREBROVASCULAR DISEASE

We will be recruiting 60 subjects in total: 30 healthy, 15 with known narrowing of the carotid artery, and 15 small vessel stroke. All subjects will undergo at least 1 optical blood flow monitoring session, and the non-healthy subjects will undergo an additional MRI.

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  • 19 Feb, 2024
  • 1 location
Epidemiological study to characterize the prevalence and distribution of lipoprotein (a) levels among patients with established cardiovascular disease.

Similar to other blood lipids, such as the "bad cholesterol", lipoprotein (a) levels were found to be associated with the risk of hardening of the arteries, known as atherosclerosis, which leads to conditions such as heart attacks, stroke, or peripheral artery disease (severe pain in legs while walking or lower …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Spironolactone for Regulating Blood Pressure after Intracerebral Hemorrhage

The purpose of this research study is to determine whether blood pressure treatment regimens with spironolactone are better than blood pressure treatment regimens without spironolactone at lowering blood pressure in hemorrhagic Stroke survivors. This study will randomize a total of 200 patients, 100 of each white and nonwhite patients, between …

  • 0 views
  • 19 Feb, 2024
  • 1 location