Parkinson's Disease Clinical Trials

Post Market Clinical Follow Up Evaluating the Infinity Deep Brain Stimulation Implantable Pulse Generator System (PROGRESS)

You are being invited to participate in a research study because you have been diagnosed with Parkinson’s disease (PD) and you underwent or have been offered a procedure called Deep Brain Stimulation (DBS) as a treatment option to manage some of your symptoms of Parkinson’s disease. The purpose of this …

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A Randomized Double-Blind Double-Dummy Active-Controlled Study Comparing the Efficacy Safety and Tolerability of ABBV-951 to Oral Carbidopa/Levodopa in Advanced Parkinson's Disease Patients

Please see Section 1 of the attached protocol.

Evaluation of in vivo Neuroinflammation in Parkinsons Disease Using 18F-NOS Positron Emission Tomography (PET/CT)

We will enroll up to 8 patients with a diagnosis of probable idiopathic Parkinsons Disease (PD cohort) and up to 8 age and gender matched Healthy Controls (HC cohort). PET/CT imaging will be used to evaluate neuroinflammation in the brain using the investigational radiotracer [18F]NOS.

Study to determine the safety tolerability pharmacokinetics and pharmacodynamics of DNL201 in subjects with Parkinsons Disease

The purpose of this research is to investigate whether DNL201 (the study drug) is safe and tolerable in Parkinson’s disease patients and to investigate how DNL201 is absorbed, broken down, and eliminated from the body. ™ 

A Randomized Placebo Surgery Controlled Double-blinded Multi-center Phase 2 Clinical Trial Evaluating Efcacy and Safety of VY-AADC02 in Advanced Parkinsons Disease with Motor Fluctuations

VY-AADC02 involves placing a gene in the brain that programs brain cells to produce an enzyme (protein) called AADC (aromatic amino acid decarboxylase) in patients with Parkinson's Disease.The study group to which you are assigned will be chosen by chance (like ipping a coin); this is known as randomization.

Language And Cognitive Impairment In Parkinson's Disease

This study is designed to determine the changes in the brain that occur during conditions of verbal stimulation in patients who have Parkinson’s Disease and Parkinson’s Disease with Dementia or Dementia with Lewy Bodies.