Obesity Clinical Trials

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Does vaginal delivery of combined hormonal contraception affect the risk of metabolic syndrome in overweight/obese women with PCOS?

Please see attached protocol under Section 1, titled "Background and Study Rationale".

A cross-sectional population study of energy expenditure in rest and exercise

Obesity is strongly regulated by energy expenditure, but the variables regulating individual levels of energy expenditure in the human population remain unknown.

Extreme Phenotypes and Obstructive Sleep Apnea

Some people who have obstructive sleep apnea are obese, and some people who have it are not obese. Also, some people who are not obese have obstructive sleep apnea. We are enrolling some people in this study who are obese and some who are not to compare differences in the …

Randomized Controlled Trial Examining the Effects of Meal Timing Among Obese Individuals

Allison and Goel's previous work on the randomized study of daytime vs. delayed eating among healthy adults, to metabolically healthy persons with obesity, but who remain at risk of developing Metabolic Syndrome (MetS) and diabetes. The study would represent the first randomized controlled experimental study in obese adults to provide …

Comparing the effects of Oral Contraceptive Pills versus Metformin in the medical management of overweight/obese women with Polycystic Ovary Syndrome

OCPs increase the risk of MetS specifically by producing an atherogenic lipoprotein phenotype, increasing blood pressure and/ or body weight while metformin modestly decreases MetS risk by decreasing body weight and improving lipid phenotype. The combination of OCP and metformin (OCP, through lowering androgens, and metformin, through improvement in insulin …