A Translational and Neurocomputational Evaluation of a D1R Partial Agonist for Schizophrenia

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Updated on 19 February 2024

Summary

The purpose of this research is to test an experimental drug CVL-562 as a possible treatment for early-course schizophrenia, schizoaffective disorder or related psychotic disorder.

This study will test whether CVL-562 can help thinking and memory in people with schizophrenia.

Description

The study involves 7 in-person visits, including an initial intake visit, 5 scan visits, and 1 follow up visit, as well as a brief phone check in 1 month after completion of the study. An investigational medication is taken prior to the scan on each of the 5 scan visits. In addition to medical assessments, subjects will participate in clinical interviews, cognitive assessments, and MRIs. Total compensation is up to $2,910.

Visit our website: https://clinicaltrials.gov/ct2/show/NCT04457310?term=PF-06412562&cond=Schizophrenia&draw=2&rank=2

Details
Condition acne,related psychotic disorders
Age 100years or below
Clinical Study IdentifierTX6692
Last Modified on19 February 2024

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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