A Phase 3 Multicenter Randomized Double- Blind Placebo- Controlled Study to Evaluate the Efficacy and Safety of AL001 in Individuals at Risk for or With Frontotemporal Dementia Due to Heterozygous Mutations in the Progranulin Gene

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    Recruiting
  • participants needed
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Updated on 19 February 2024

Summary

The research study is being conducted to test the safety and tolerability (i.e., possible side effects) of an investigational drug called AL001 and to find out what effects AL001 has on the body. This is for people who have a confirmed progranulin gene mutation that causes frontotemporal dementia (FTD). Study particiants will need to have a spouse, family member, or friend participate in this study with them as a study partner. This person should have at least 5 hours of in-person contact with the study participant each week and will be responsible for providing information about memory and daily functioning of the study participant to the study doctor or study staff during study visits. The study partner must also agree to participate in this study by signing a separate Informed Consent Form.

Details
Condition Medical Research
Age 99years or below
Clinical Study IdentifierTBD
Last Modified on19 February 2024

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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