Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)
How will study participants contribute to HVTN 405/HPTN 1901? 
  • Participants will attend one required clinic visit and will have the option to attend additional clinic visits two, four and twelve months after the initial visit. 
  • Each visit includes a questionnaire, blood draw and optional nasal sampling. 
  • Individuals who have not fully recovered from their infection (i.e., still have symptoms or had a positive test within the preceding two weeks) will not be enrolled. 

Study details
    COVID-19

TX6453

22 September 2026

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Informed consent
Introduction
You are being asked to participate in a research study. Before you decide to participate in this study, it is important that you understand why the research is being done and what it will involve. This form is designed to give you the information about the study so you can decide whether to be in the study or not. Please take the time to read the following information carefully. You should ask the researcher if there is anything that is not clear or if you need more information.
Study Participation
If you agree to participate in this study, you will be asked to:
  • Attend screening visit to determine eligibility
  • Attend 6–8 clinic visits over approximately 12 weeks
  • Provide blood samples at designated visits
  • Complete questionnaires about your symptoms and quality of life
  • Take study medication or placebo as directed
  • Report any side effects or health changes to the study team

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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