A Randomized Placebo Surgery Controlled Double-blinded Multi-center Phase 2 Clinical Trial Evaluating the Efficacy and Safety of VY-AADC02 in Advanced Parkinson's Disease with Motor Fluctuations
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- STATUS
- Not Recruiting
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- participants needed
- 4
Summary
The purpose of this study is to test the safety and efficacy of an experimental gene transfer therapy called VY-AADC02 in adult subjects with advanced Parkinson's Disease (PD). AADC is a naturally occurring protein found in the brain that converts levodopa (PD medication) to dopamine. The study product , delivered directly into the brain via a cannula with the imaging medium gadolinium, will increase production of AADC, which may increase dopamine levels. This in turn may provide improvement in PD symptoms. Please see pages 4-5 of the Protocol,"Study Rationale," for a more detailed discussion.
Details
| Condition | Medical Research |
|---|---|
| Age | 99years or below |
| Clinical Study Identifier | 03562494 |
| Last Modified on | 19 February 2024 |
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