Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

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Updated on 19 February 2024

Summary

The purpose of this research study is to assess whether lowering of your cholesterol blood level can reduce your risk for major cardiovascular events (for example, heart attack or stroke) when evolocumab is taken in addition to your current medical therapy as directed by your doctor, which may include a medication for the treatment of abnormal cholesterol blood levels called “statins”

Description

You are being asked to take part in this study because your doctor thinks you are at high risk for experiencing a cardiovascular event (like a heart attack or stroke). Elevated cholesterol, in particular low-density lipoprotein cholesterol (LDL-C), can lead to obstructing fatty deposits in blood vessels that can greatly increase your risk of developing cardiovascular disease or experiencing a cardiovascular event.

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Details
Condition stroke,heart,cardiovascular
Age 18years - 99years
Clinical Study IdentifierTX6337
Last Modified on19 February 2024

Eligibility

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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