SMaRT Blood: Single-unit versus Multiple-unit pRBC Transfusion in non-acute postpartum anemia

Blood transfusion is often recommended for women who have anemia (low blood counts) after delivering a baby. Currently, many doctors give 2 units, or packets, of blood because they expect that everyone will need 2. However, it may be better to only give 1 unit at a time to raise blood counts and relieve the symptoms of anemia, such as dizziness or feeling tired. The purpose of this study is to help us understand whether giving only 1 unit of blood at a time can reduce the total number of units of blood needed to raise low blood counts after delivery. The study will compare the effects of giving 1 unit or 2 units of blood at a time. If you decide to participate, you will be in one of two groups – a group receiving 1 unit at a time or a group receiving 2 units at a time. We are asking women to volunteer for the study if they are at least 18 years of age, they have delivered a baby, and have been recommended to receive a blood transfusion at the Hospital of the University of Pennsylvania.