Efficacy of DE-MRI-Guided Fibrosis Ablation vs. Conventional Catheter Ablation of Atrial Fibrillation: The DECAAF II Study
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- STATUS
- Enrolling By Invitation
Summary
You are being asked to participate in this study because you have atrial fibrillation and are planning to undergo an ablation procedure to treat this heart rhythm irregularity.
Description
Atrial fibrillation (AF) is a condition of the heart that consists of disorganized electrical activity involving the entire atria (upper chambers) of the heart. AF is more prevalent with advancing age and is associated with structural heart disease including high blood pressure, systolic and diastolic ventricular dysfunction (dysfunction of the lower heart chambers), and disease of the heart valves. It represents a significant public health problem in the general population around the world. People with AF are more likely to have a stroke, a diminished quality of life, and a greater chance of heart failure or other conditions of the heart. Research has shown that people with AF have scarring or some amount of damaged tissue in their heart’s upper chamber. This scarred tissue can determine whether AF continues or whether it can be stopped. The more fibrosis, or scar tissue, that is present in the atrium, the more likely it is for the arrhythmia to continue. While conventional catheter ablation has been successful for rhythm control in AF, the success of this procedure is significantly affected by the amount of scar tissue at the time of catheter ablation. Some doctors target specific areas of the fibrotic or scarred tissue in addition to the regular ablation procedure. This type of ablation uses images of the fibrotic areas on your heart to help target the fibrosis, (scarred areas), during the ablation procedure.
FAQ
Details
| Condition | atrial ablation |
|---|---|
| Age | 18years - 60years |
| Clinical Study Identifier | TX6313 |
| Last Modified on | 19 February 2024 |
Eligibility
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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