Identification of neoantigen-specific T cell responses in cancer patients within the Penn Medicine BioBank
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- STATUS
- Enrolling By Invitation
Summary
You are being asked to participate in this research investigation because you have expressed an interest in participating in a study to better understand how the immune cells of the body recognize and fight cancer.
Description
The main purpose of this study is to identify immune fighting cells known as T cells that recognize proteins expressed by cancer cells. The results of this study will be used to develop new treatments for cancer patients using the body’s immune system. The study involves providing a blood sample to be used in the laboratory for immune system research at the University of Pennsylvania. Your cells will be collected and purified by members of the Vonderheide lab. Your immune cells known as white blood cells will be analyzed to determine your Human Leukocyte Antigen (HLA) type. HLA is a unique genetic marker or “fingerprint” on white blood cells that are important for how your immune system fights infections and cancer. Your white blood cells will then be used in the laboratory to study how the cells of the immune system recognize and kill cancer cells. No experimental treatments or procedures will be performed on you. These research results will not be of direct benefit to you, however, the results may provide important benefits to patients with cancer in the future. With this in mind, you are being asked to serve as a volunteer to donate white blood cells for this research study.
FAQ
Details
| Condition | cancer |
|---|---|
| Age | 18years - 90years |
| Clinical Study Identifier | TX6312 |
| Last Modified on | 19 February 2024 |
Eligibility
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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.
Learn moreIf you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.
Learn moreComplete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.
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