UPCC 19418: A Phase 1/2a Dose-Finding Study of PT-112 in Patients with Relapsed or Refractory Multiple Myeloma

  • STATUS
    Enrolling By Invitation
  • participants needed
    10
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Updated on 19 February 2024

Summary

Multicenter, open-label study of PT-112 in patients with relapsed/refractory MM. The study will be conducted in two parts. The first part of the study involves dose-escalation, in which successive cohorts of patients will receive escalating doses of PT-112 until the maximum tolerated dose (MTD) is reached. The second part of the study involves treatment of an expansion cohort to confirm the tolerability of treatment at the recommended dose and evaluate evidence of treatment efficacy. All patients in the expansion cohort will be tested for genetic alterations in an effort to identify potential biomarkers for response to PT-112 treatment.

Details
Condition myeloma
Age 99years or below
Clinical Study Identifier03288480
Last Modified on19 February 2024

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If you need help finding a study or have any questions, please contact us at psom-ocr@pobox.upenn.edu

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