If you agree to participate your participation will involve two visits. Both visits will take place at the Center for Human Phenomic Science (CHPS; formerly the Clinical and Translational Research Center) at the Hospital of the University of Pennsylvania. You will asked to wear an activity monitoring device called an actiwatch for one week at home. You will be asked to complete a sleep diary throughout the week. One evening, two technicians will come to your home to set you up with equipment to record your sleep overnight.
For your second visit you will come to the CHPS at 5:00 pm and be checked into the hospital. During the rest of the evening you will be free to engage in activities of your own choosing including watching TV, reading, or talking on your personal phone. During the night you are in the CHPS, your sleep will be monitored.
At 8 am, a neurologist experienced with this procedure will conduct a neurological exam prior to performing a lumbar puncture (“spinal tap”) to collect your cerebrospinal fluid (“CSF”). The exam will be used to determine if you have any medical conditions that would increase the risk of the lumbar puncture.
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