A Phase 1/2 Study of Oral LOXO-292 in Patients

  • STATUS
    Recruiting
  • participants needed
    5
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Updated on 19 February 2024

Summary

LOXO-292 is a highly potent and specific inhibitor of the RET RTK, with minimal inhibition of other kinase and non-kinase targets, and therefore may be of benefit to patients with tumors (such as NSCLC, MTC, PTC, and colon or breast carcinomas) that harbor RET alterations and/or depend on RET activation. This Phase 1/2 study of LOXO-292 is required to understand the PK, safety, and maximum tolerated dose (MTD) for LOXO-292 in patients and to permit the preliminary assessment of efficacy.

Details
Condition TBD
Age 99years or below
Clinical Study Identifier03157128
Last Modified on19 February 2024

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