Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)

Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)

Dapagliflozin Effect on symptoms and blomarkers in patients with Heart Failure (DEFINE-HF)

Recruiting
18 years and older
All
Phase N/A
Dapagliflozin lowers glucose (sugar) levels in the blood by blocking the effect of specific molecules (small particles) in your body called sodium-glucose transporters. Under normal circumstances, the sodium-glucose transporters in the kidney prevent glucose in your blood stream from leaving your body through your urine. Dapagliflozin inhibits the sodium-glucose transporters and lowers your blood glucose by allowing glucose removal through the urine. Dapagliflozin may also mildly decrease body weight and lower blood pressure in certain patients. In this study, dapagliflozin will be compared with placebo. The placebo will look like dapagliflozin but is inactive. Patients will be randomly chosen to receive either dapagliflozin or placebo and neither the physician nor the patient will know which they are receiving until the entire study is completed. Patients will continue to take to take their regular diabetes medications, unless their diabetes is very well controlled in which case their dose of insulin or oral diabetes medication may be decreased.
Study details
    heart failure

TBD.

Saint Luke's Hospital of Kansas City is sponsoring this study from funding provided by AstraZeneca Pharmaceuticals LP

19 February 2024

Step 1 Get in touch with the nearest study center
Message sent successfully.
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.
Sign up

Send a message

Enter your contact details to connect with study team


Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Preferred way of contact
Please provide your preferred way of contact
Race
Select race
Ethnicity
Select ethnicity
Other language

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.