Measurement of Pulmonary Inflammation Using F-NOS Positron Emission Tomography (PET/CT) in E-cigarette Users

  • STATUS
    Recruiting
  • participants needed
    60
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Updated on 19 February 2024

Summary

This is a 1 – 2 month study examining the extent of lung inflammation between e-cigarette smokers, cigarette smokers, and non-smokers using a new radio tracer, FNOS. FNOS is an experimental radio tracer used to look for inflammation in different parts of the body. The tracer that we will be using has been shown to be safe for use on both humans and animals and allows us to examine the level of inflammation in the lungs. The level of radiation you will be exposed to is very minimal and unlikely to have any effect on you. Although some evidence suggests that e-cigarettes do not affect lung inflammation, there are very few studies that have produced data to support that. The findings of this PET scan will help scientists better understand the effects of e-cigarette smoking on the lungs.

Description

In this study, you will participate in only 2 visits to be scheduled over the course of approximately 6 weeks: 
1) a combined consent and screening visit (~3 hours)
2) one PET/CT lung scan (~3 hours)

FAQ

Compensation will be provided upon successful completion of each study visit: $50 consent/screen and $150 PET/CT lung scan

Details
Condition Nicotine Dependence,Lung Inflammation,healthy volunteer
Age 18years - 45years
Clinical Study IdentifierNCT03721822
Last Modified on19 February 2024

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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