UPCC 04717: Phase I open label dose-escalation study to evaluate the safety expansion persistence of a single dose of UCART19 (allogeneic engineered T-cells expressing anti-CD19 chimeric antigen receptor) administered intravenously in patients with relapsed or refractory CD19 positive B-cell acute lymphoblastic leukaemia (B-ALL)

  • STATUS
    Enrolling By Invitation
  • participants needed
    10
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Updated on 19 February 2024

Summary

The main aims of this study are to test the safety of up to 4 different doses of UCART19, and to identify the best dose of UCART19, by measuring what has happened to the leukemia cells at day 28 (28 days after the administration of UCART19), day 84 (84 days after the administration of UCART19) and the overall response during the study period.

Details
Condition ['B-cell Acute Lymphoblastic Leukemia']
Age 99years or below
Clinical Study Identifier02746952
Last Modified on19 February 2024

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If you need help finding a study or have any questions, please contact us at psom-ocr@pobox.upenn.edu

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