Low-Dose Naltrexone to Improve Physical Health in Patients with Vasculitis (LoDoNaVasc)

  • STATUS
    Recruiting
Send
Updated on 19 February 2024

Summary

The purpose of this study is to see whether a drug called naltrexone improves health-related quality of life in patients with vasculitis. Naltrexone is a prescription drug approved for a different reason at a higher dose than the dose used in this study. However, “low dose naltrexone” is widely used, without insurance coverage, for a wide range of conditions associated with pain or fatigue. We hope to learn more about the impact of low dose naltrexone on the symptoms caused by vasculitis.

Description

Patients must have a diagnosis of vasculitis and significantly low quality of life caused by some combination of pain, fatigue, poor physical health, and difficulty carrying out activities. Medication used to treat vasculitis, pain, and fatigue must be stable for 12 weeks before a patient can enroll in the study.

Details
Condition Polyarteritis nodosa, Vasculitis, Microscopic Polyangiitis (MPA), Giant Cell Arteritis ( GCA), Takayasu's Arteritis (TAK), Granulomatosis with Polyangiit, Eosinophilic Granulomatosis wi
Age 18years - 90years
Clinical Study Identifier03482479
Last Modified on19 February 2024

Eligibility

How to participate?

Step 1 Connect with a study center
Message sent successfully.
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Preferred way of contact
Race
Ethnicity
Other language

Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

Learn more

If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

Learn more

Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

Learn more

Similar trials to consider

Not finding what you're looking for?

Every year hundreds of thousands of volunteers step forward to participate in research. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.

Sign up as volunteer
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.