Acute and Long-term Effects of E-Cigarette Aerosol Inhalation on Biomarkers of Endothelial Function and Vascular Reactivity

Acute and Long-term Effects of E-Cigarette Aerosol Inhalation on Biomarkers of Endothelial Function and Vascular Reactivity

Acute and Long-term Effects of E-Cigarette Aerosol Inhalation on Biomarkers of Endothelial Function and Vascular Reactivity

Recruiting
18-35 years
All
Phase N/A
Non-smokers: these participants will complete 1 study visit. The study visit will consist of 2 blood draws, 2 MRIs and 1 smoking encounter of a non-nicotine e-cigarette. These visits last around 3-3.5 hours. Smokers: these participants will complete 2 study visits. Of the smokers, there are 2 cohorts of interest: conventional and e-cigarette smokers. The baseline and 12 month visits will consist of 1 blood draw and one MRI. Each visit will last about 1.5 hours. Prior to enrollment, subjects will be asked to undergo a brief telephone screening to confirm eligibility. This will be done with either study coordinator, Alyssa Johncola or Kelly Sexton.
Study details
    healthy Volunteers
    smokers
    healthy subjects
    Healthy
    healthy controls
    Smoking
    Healthy volunteer
    healthy
    healthy volunteer
    healthy volunteers
    healthy subjects
    healthy
    healthy controls
    healthy controls
    smoker
    e-cig
    e-cigarette

NCT03479203

19 February 2024

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