T-Cell Response to Vaccination

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Updated on 10 December 2025

Summary

The purpose of this study is to see how your body responds to a vaccine and how your body forms a protective response after vaccination. In this study we will use the yellow fever vaccine, an FDA approved vaccine that is commonly given to people traveling to certain parts of Africa and South America.

Description

The study consists of a screening visit followed by 9 study visits. From the time of screening, you will be in this study for between 8-12 months. The study include: Screening visit (approx 1 hour), Study visit 1 - Luekopheresis (approx 2.5 hours), Study Visit 2 - Vaccination (approx 45 mins), Study Visits 3-8 - Blood Draws (approx 30 mins), Study Visit 9 - Leukopheresis (approx 2.5 hours).

FAQ

The compensation for this study is broken down to $25 per visit for first 8 study visits and a $100 bonus for completing all 8 study visits ($300 total). You will receive an additional $100 for completing study visit 9 ($400 total). To participate in this study you must be between 18-65 years old. You may not participate in this study if you have allergies to eggs, latex, or gelatin OR if you have an immune suppressive disease or is taking an immune suppresive medication.

Details
Condition healthy Volunteers,healthy subjects,Healthy,Healthy volunteer,healthy,healthy volunteer,healthy volunteers,healthy subjects,healthy
Age 18years - 65years
Clinical Study IdentifierTX4750
Last Modified on10 December 2025

Eligibility

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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