Hormone effects in smoking addiction

  • STATUS
    Recruiting
  • participants needed
    150
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Updated on 19 February 2024

Summary

The purpose of this study is to determine whether progesterone is helpful in reducing withdrawal symptoms, cigarette cravings, and smoking behavior. This study will also use brain imaging to measure the possible effects of progesterone on your brain chemicals. Healthy male and non-pregnant female smokers are invited to screen for study participation.

Description

Smokers between the ages of 18-50 who smoke at least 10 cigarettes per day will be asked to undergo a screening visit where they will be asked to complete questionnaires about their mental health and complete lab assessments. All qualified participants will be asked to participate in two 5-day long out-patient test phases where they will undergo 3 brain-imaging scans, blood draws, and remain abstinent from smoking. Participants will be compensated for study participation.

FAQ

You may qualify if you are: -Between the ages of 18-50; Right-handed; Not on medication for depression, anxiety, pain or sleep disorders; medically healthy. Please contact the study team directly for more information and to determine eligibility.

Details
Condition healthy Volunteers, smokers, healthy subjects, Healthy, healthy controls, nicotine, Healthy Control, Healthy volunteer, healthy, healthy volunteer, healthy volunteers, healthy subjects, healthy, healthy controls, healthy controls
Age 18years - 50years
Clinical Study IdentifierTX1035
Last Modified on19 February 2024

Eligibility

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Additional screening procedures may be conducted by the study team before you can be confirmed eligible to participate.

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If you are confirmed eligible after full screening, you will be required to understand and sign the informed consent if you decide to enroll in the study. Once enrolled you may be asked to make scheduled visits over a period of time.

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Complete your scheduled study participation activities and then you are done. You may receive summary of study results if provided by the sponsor.

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